Call for Proposal by Department of Biotechnology for research in Cardiovascular health and diseases

DBT call for proposal
Department of Biotechnology invites Expression of Interest (EOI) focusing on “Cardiovascular health and diseases’ as a part of Chronic & Lifestyle Diseases Program for gaining deep insights into the pathophysiology of cardiovascular complications and understanding cardiac functions and developing early risk-assessment strategies to prevent the multi-dimensional complexities associated with CVD.

Eligibility

Scientist/Clinicians/Biotechnologies/Clinical researchers engaged in public and private Academic institutions/Universities/ R&D centres recognized by DSIR.

The LoI should be signed by all the PI(s)/Co-PI(s) and forwarded by the Executive Head of the proposed host institution(s).


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How to apply

Submission of EOI in the prescribed format only duly forwarded by the executive head of the institution through email in PDF (one consolidated file with Annexure) and MS-Word file formats [not more than max. 8-10 pages] to email id given in the official notification. 

Format for EOI 

  • Proposal Title 
  • Details of institutions and investigators involved in project (including Project Coordinator/ PIs/co-PIs) 
  • Area/Topic of research (to mention any 1 out of 3) 
  • Scientific Rational with specific biological questions to address the unmet need  
  • Clear-cut goals addressing the need 
  • Brief strategy to execute the targeted goals 
  • Role & responsibility of each collaborating partner  
  • Brief CV  (1 page) of Project Coordinator/collaborating PIs with a maximum number of 5 publications strictly related to the proposed topic  
  • Approximate Budgetary requirement  to accomplish the targeted goals 

Specific areas in which EOI could be submitted:

Cardiovascular consequences of Viral Infection including post-COVID impact

  • Molecular mechanism of viral interaction with cardiac myocytes, cohort studies on post COVID impact on CV health, role of coagulation pathway in post COVID CV morbidity.

Models for understanding cardiac function and drug discovery

  • In vivo mimetic micro-physiological systems pertaining to spatiotempral alterations in gene/protein/metabolities to be used as platforms for drug discovery, modeling the diseases biology.

Cardio-metabolic Health-Unmet Need and prevention strategies
  • Identifying the highest-risk individuals (in paeditric, adolescent and adult populations, among others) for CVD and heart failure.
  • Earlier identification of patients at risk - novel biomarker identification or predective algorithms to assess changes in risk
  • Prognostic or Predictive biomarker identification (genetic, epigenetic, lipidomic, proteomic metabolomics etc) and validation leading to earlier recognition of risk and/or protective factors.

Last date to apply: 31-December-2024

Official notification: Official notification





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